Osmosis Jones (voice)

Drix (voice)

Mayor Paul Spryman / Hector's Mom (voice)

Hector Cruz (voice)

Maria Amino (voice)

Police Chief Gluteus (voice)

Travis Lum (voice)

Ellen Patella (voice)

Brain Advisor #1 (voice)

Dander (voice)

The Mole (voice)

General Malaise (voice)

Christine Kolchuck (voice)

Rescue Cell (voice)

Mayor Santorini (voice)

Nick O'Teen (voice)

Ashley / Carbon Monoxide (voice)

Strepfinger (voice)

Cilia Tyson (voice)

Hector's Dad (voice)

Captain Quinine (voice)

Naurine / Celly Katz (voice)

Aunti Histamine (voice)

Mumsy Glop (voice)

Drixeen (voice)

Cop (voice)

Rota (voice)

Muscle Cell (voice)

Smirch (voice)

Cafeteria Lady (voice)

Number 2 / Sticky Flagella (voice)

Shwee (voice)

Penicillin G (voice)

Jude (voice)

Rudy (voice)

Jumbo (voice)

Sal Monella (voice)

Sylvian Fisher (voice)

Loretta Epstein (voice)

Shane (voice)

Brittany Estrogen (voice)

Ricardo Amino (voice)

Father Glop (voice)

Cryo (voice)