Granny Cuyler (voice)

Rusty Cuyler (voice)

Narrator / Denny (voice)

Dan Halen (voice)

Aunt Lil (voice)

Sheriff (voice)

Early Cuyler (voice)

Reverend (voice)

Miguel

Tammy (voice)

Pastor Nubbins (voice)

Early Cuyler (voice)

Ga-Ga-Pee-Pap Cuyler (voice)

Macho Man Randy Cuyler (voice)

Therapist (voice)

Durwood (voice)

Ra (voice)

Announcer (voice)

T-Pain (voice)

Kevin Gillespie (voice)

Paul Stanley GPS (voice)

Talking Squid (voice)

David Allan Coe (voice)

Chad Ochocinco (voice)

Mudsy (voice)

Coolio (voice)

Wee Man (voice)

Ned Hastings (voice)

Authentic Mexican

(voice)

Snow Daddy (voice)

Judge Jammer (voice)

(voice)

Self

Don Barnes (voice)

Danny Chauncey (voice)

Larry Junstrom (voice)

Eric "Butterbean" Esch (voice)

Mammy (voice)

Thunderclap Cherokee Antoine (voice) (uncredited)

Domingo S. Ortiz (voice)

John Bell (voice)

Todd Nance (voice)

Dave Schools (voice)

John Hermann (voice)

Jimmy Herring (voice)

Pnut (voice)

Steve Earle (voice)

Ray Wylie Hubbard (voice)

Shooter Jennings (voice)

Nikki Lane (voice)

Mojo Nixon (voice)

Roger Alan Wade (voice)

Lucinda Williams (voice)

Dr. Anastasia Evertree (voice)